How T-cells navigate the rough-and-tumble environment of the bloodstream

Helper T cells move toward inflamed tissue using membrane protrusions that stabilize them and provide traction on the vasculature. Using high-resolution microscopy and global molecular analysis, scientists show that immature T cells lack these protrusions but that maturing T-cells switch on a gene expression program to create material to construct them. https://www.sciencedaily.com/releases/2017/12/171226154213.htm